Outros Testes com Aplicação Prática Menos Disseminada

espermatozoides. Os anticorpos antiespermatozoides exercem efeitos

heterogêneos sobre a capacidade dos espermatozoides para fertilizar.

 

Técnicas

 

A análise pode ser realizada no soro, plasma seminal ou diretamente aos

espermatozoides. Os anticorpos indiretos são utilizados no teste de ELISA,

e o uso de Immunobeads de maneira direta detectam a presença de

imunoglobulinas (IgA e IgG) na cabeça e parte proximal da cauda dos

espermatozoides considerando um possível fator de infertilidade.

 

Indicações

 

• Diagnóstico de doenças de origem imunológica, presença isolada de

astenospermia ou aglutinação de espermatozoides;

• Teste pós-coito negativo;

• Infertilidade conjugal sem causa aparente;

• Fatores de risco para a formação de anticorpos, como trauma, torção,

biópsia, orquite, câncer testicular e vasectomia.

Recomendamos a indicação de ICSI no tratamento de infertilidade

por presença de anticorpos antiespermatozoides como fator principal

da infertilidade.

 

Outros Testes com Aplicação Prática Menos

 

Disseminada

 

Além disso, outros testes estão sendo utilizados no manejo da infertilidade

masculina, mas são ainda muito recentes e com a necessidade de maiores

estudos para uma correta indicação e conduta, por exemplo: dosagens de

creatina quinase e análise de radicais livres de oxigênio (ROS).

Procedimentos para seleção do “melhor” espermatozoide também estão

sendo empregados, como a utilização de ácido hialurônico, testes de

maturação da membrana do espermatozoide, avaliação apoptótica, seleção

de espermatozoides por meios magnéticos, análise morfológica ampliada e, por último, testes mais recentes que detectam a presença de papilomavírus

(HPV) no sêmen.

 

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